Photo: Leon Bennett/Getty

Christina Applegateis looking ahead to the upcomingScreen Actors Guild Awardswith bittersweet emotions.
TheDead to Meactress, whoconfirmed her MS diagnosisin 2021, revealed that the upcomingSAG Awardswill most likely be her last as she continues to deal with the impacts from the disease.
“It’s my last awards showas an actor probably, so it’s kind of a big deal,” Applegate, 51, toldThe Los Angeles Timesin an interview published on Tuesday.
She added, “Right now, I couldn’t imagine getting up at 5 a.m. and spending 12 to 14 hours on a set; I don’t have that in me at this moment.”
Though acting is no longer on her radar, Applegate does have her next career move in mind: “Doing a s— ton of voice-overs to make some cash to make sure that my daughter’s fed and we’re homed,” she told theLA Times.
Saeed Adyani/NETFLIX

Applegate’s remarks come nearly two years aftershe was diagnosed with multiple sclerosis. At the time, she was filmingDead to Me’s third and final season, which forced her to take a hiatus from taping and undergo treatment.
Speaking toThe Times,the actress saluted the “incredible” crew, the series' showrunner, and her costars, saying they were “Jen and Judy combined into a human, in the most perfect and beautiful way possible” — a reference to the close friendship between her character and that ofLinda Cardellini, who portrays Judy Hale.
Applegate also revealed how difficult it was to watch the third season once it had been released on Netflix.
“I don’t like seeing myself struggling,” she said. “Also, I gained 40 pounds because of inactivity and medications, and I didn’t look like myself, and I didn’t feel like myself.” She watched alone, stopping periodically when it became too painful. “At some point I was able to distance myself from my own ego, and realize what a beautiful piece of television it was. All the scenes I wasn’t in were so much fun to see and experience for the very first time.”
RELATED VIDEO: Christina Applegate Tears Up During Hollywood Walk of Fame Ceremony Speech 1 Year After MS Diagnosis
In November, Applegate reflected on filming the series during an interview withVariety, revealing it was “as hard as you would possibly think it would be.”
Never miss a story — sign up forPEOPLE’s free daily newsletterto stay up-to-date on the best of what PEOPLE has to offer, from juicy celebrity news to compelling human interest stories.
The actress, whoreceived a star on the Hollywood Walk of Fameon Nov. 14, explained that she’s seeking “a place that will allow me to [work five hours] if I’m not the star,” and that starring in something might be off the table in the future.
“There’s no way I could do the work that I just came off again. I mean, it wassohard,” she said, adding that her focus nowadays is her family, specifically her 12-year-old daughter Sadie Grace LeNoble, who she shares with husband Martyn LeNoble.
“I’m pretty convinced that this was it, you know? But who knows — I’m probably gonna get real bored of being in my room. I’d like to develop stuff, I’d like to produce stuff,” she added. “I’ve got a lot of ideas in my mind, and I just need to get them executed.”
The 29th Screen Actors Guild Awards will be held on Sunday, Feb. 26.
source: people.com